|Other Names||Chymotrypsin-like elastase family member 2B, Elastase-2B, CELA2B, ELA2B|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts upon elastin.|
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Provided below are standard protocols that you may find useful for product applications.
Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2B is secreted from the pancreas as a zymogen. In other species, elastase 2B has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues.
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)Szepessy, E., et al. Pancreatology 6 (1-2), 117-122 (2006) Fletcher, T.S., et al. Biochemistry 26(23):7256-7261(1987)
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