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CCDC62 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6P9F0 |
|---|
| Gene ID | 84660 |
|---|---|
| Other Names | Coiled-coil domain-containing protein 62, Protein TSP-NY, Protein aaa, CCDC62 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CCDC62 |
|---|---|
| Function | Nuclear receptor coactivator that can enhance preferentially estrogen receptors ESR1 and ESR2 transactivation. Modulates also progesterone/PGR, glucocorticoid/NR3C1 and androgen/AR receptors transactivation, although at lower level; little effect on vitamin D receptor/VDR. Required for normal spermiogenesis. It probably plays a role in acrosome formation (By similarity). |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Mainly nuclear |
| Tissue Location | Highly expressed in adult testis. Expressed in both prostate epithelial and stromal cells, with predominant expression in epithelial cells (at protein level) (PubMed:19126643). Not detected in prostate by RT-PCR (PubMed:19165854). Overexpressed in various cancers {ECO:0000269|PubMed:19126643, ECO:0000269|PubMed:19165854, ECO:0000269|Ref.1, ECO:0000269|Ref.4} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
The function of this protein has not been specifically defined.
References
Domae, S., et al. Int. J. Cancer 124(10):2347-2352(2009)Chen, M., et al. Carcinogenesis 30(5):841-850(2009)Chen, M., et al. Prostate 68(12):1273-1282(2008)
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