ENTPD8 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5MY95 |
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Gene ID | 377841 |
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Other Names | Ectonucleoside triphosphate diphosphohydrolase 8, E-NTPDase 8, NTPDase 8, NTPDase8, ENTPD8 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ENTPD8 |
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Function | Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. |
Cellular Location | Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
ENTPD8 is canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. It is ectonucleoside NTPDases catalyze the hydrolyzis of gamma-and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. ENTPD8 has activity toward ATP, ADP, UTP and UDP, but not toward AMP.
References
Munkonda, M.N., et al. Biochem. Pharmacol. 74(10):1524-1534(2007)Fausther, M., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 292 (3), G785-G795 (2007) Knowles, A.F., et al. Biochemistry 45(23):7323-7333(2006)
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