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ATXN2L Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WWM7 |
|---|
| Gene ID | 11273 |
|---|---|
| Other Names | Ataxin-2-like protein, Ataxin-2 domain protein, Ataxin-2-related protein, ATXN2L, A2D, A2LG, A2LP, A2RP |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ATXN2L |
|---|---|
| Synonyms | A2D, A2LG, A2LP, A2RP |
| Function | Involved in the regulation of stress granule and P-body formation. |
| Cellular Location | Membrane; Peripheral membrane protein. Cytoplasm. Nucleus speckle. Cytoplasmic granule. Note=Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition of methylation alters nuclear localization (PubMed:25748791). Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791). |
| Tissue Location | Expressed at high levels in thymus, lymph node, spleen, fetal kidney and adult testis. Constitutively associated with MPL and EPOR in hematopoietic cells. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ATXN2L encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders.
References
Imielinski, M., et al. Nat. Genet. 41(12):1335-1340(2009)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Nonhoff, U., et al. Mol. Biol. Cell 18(4):1385-1396(2007)
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