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C19orf20 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6ZTW0 |
|---|
| Gene ID | 91978 |
|---|---|
| Other Names | Tubulin polyglutamylase complex subunit 1, PGs1, TPGS1, C19orf20 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TPGS1 (HGNC:25058) |
|---|---|
| Synonyms | C19orf20 |
| Function | Subunit of the tubulin polyglutamylase complex (TPGC). The complex mediates cilia and flagella polyglutamylation which is essential for their biogenesis and motility (Probable). May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000250|UniProtKB:Q99MS8}. Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q99MS8}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q99MS8}. Cytoplasm, cytoskeleton, flagellum basal body {ECO:0000250|UniProtKB:Q99MS8}. Cell projection, axon {ECO:0000250|UniProtKB:Q99MS8}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q99MS8}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q99MS8} Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Note=Associated with microtubules from neurites, centrosomes, basal bodies and axonemes. {ECO:0000250|UniProtKB:Q99MS8} |
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Provided below are standard protocols that you may find useful for product applications.
Background
C19orf20 may act in the targeting of the tubulin polyglutamylase complex. C19orf20 required for the development of the spermatid flagellum.
References
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Regnard, C., et al. J. Cell. Sci. 116 (PT 20), 4181-4190 (2003)
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