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CNO6L Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96LI5
Clone Names 91208306
Peptide ID 91208306
Additional Information
Gene ID 246175
Other Names CCR4-NOT transcription complex subunit 6-like, Carbon catabolite repressor protein 4 homolog B, CNOT6L, CCR4B
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CCR4B
Function Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. May be involved in the deadenylation-dependent degradation of mRNAs through the 3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA. Its mRNA deadenylase activity can be inhibited by TOB1. Mediates cell proliferation and cell survival and prevents cellular senescence.
Cellular Location Cytoplasm. Nucleus.
Tissue Location Highly expressed in placenta, skeletal muscle, pancreas, testis and leukocytes. Weakly expressed in heart, spleen and thymus.
Research Areas
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$ 80.00
Cat# BP5207a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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