|Other Names||Proenkephalin-B, Beta-neoendorphin-dynorphin, Preprodynorphin, Alpha-neoendorphin, Beta-neoendorphin, Big dynorphin, Big Dyn, Dynorphin A(1-17), Dyn-A17, Dynorphin A, Dynorphin A(1-13), Dynorphin A(1-8), Leu-enkephalin, Rimorphin, Dynorphin B, Dyn-B, Dynorphin B(1-13), Leumorphin, Dynorphin B-29, PDYN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
PDYN is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine.
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Soranzo, N., et al. Nat. Genet. 41(11):1182-1190(2009)Greisenegger, E.K., et al. Clin. Exp. Dermatol. 34(6):728-730(2009)
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