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RNASEK Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q6P5S7
Additional Information
Gene ID 440400
Other Names Ribonuclease kappa, RNase K, RNase kappa, 31--, RNASEK
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNASEK
Function Endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. Hydrolyzes UpU bonds at a lower rate (PubMed:17881363). Regulates the activity of vacuolar (H+)-ATPase (V- ATPase) which is responsible for acidifying and maintaining the pH of intracellular compartments (PubMed:26212330). Required at an early stage of receptor-mediated endocytosis (PubMed:26212330).
Cellular Location Endomembrane system; Multi-pass membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250|UniProtKB:Q3ZC23}; Multi-pass membrane protein
Tissue Location Widely expressed..
Research Areas
Citations (0)
citation

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Background

RNASEK is endoribonuclease which preferentially cleaves ApU and ApG phosphodiester bonds. RNASEK hydrolyzes UpU bonds at a lower rate.

References

Economopoulou, M.A., et al. Nucleic Acids Res. 35(19):6389-6398(2007)Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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$ 277.78
Cat# BP5259c
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