RPA43 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q3B726 |
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Gene ID | 221830 |
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Other Names | DNA-directed RNA polymerase I subunit RPA43, Twist neighbor protein, TWISTNB |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | POLR1F (HGNC:18027) |
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Function | Component of RNA polymerase I (Pol I), a DNA-dependent RNA polymerase which synthesizes ribosomal RNA precursors using the four ribonucleoside triphosphates as substrates. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters. |
Cellular Location | Nucleus, nucleolus. |
Tissue Location | Widely expressed. Expressed in all fetal and adult tissues tested, with highest expression in fetal lung, liver, and kidney, and low expression in all adult tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
RPA43 is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It is component of RNA polymerase I which synthesizes ribosomal RNA precursors. Through its association with RRN3/TIF-IA may be involved in recruitment of Pol I to rDNA promoters.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)Yuan, X., et al. EMBO Rep. 3(11):1082-1087(2002)Kosan, C., et al. Cytogenet. Genome Res. 97 (3-4), 167-170 (2002)
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