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SLC25A19 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9HC21
Additional Information
Gene ID 60386
Other Names Mitochondrial thiamine pyrophosphate carrier, Mitochondrial uncoupling protein 1, Solute carrier family 25 member 19, SLC25A19, DNC, MUP1
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC25A19 (HGNC:14409)
Function Mitochondrial transporter mediating uptake of thiamine diphosphate into mitochondria. It is not clear if the antiporter activity is affected by the membrane potential or by the proton electrochemical gradient.
Cellular Location Mitochondrion membrane; Multi-pass membrane protein
Tissue Location Expressed in all tissues examined except for placenta. Highest levels in colon, kidney, lung, testis, spleen, and brain.
Research Areas
Citations (0)
citation

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Background

SLC25A19 encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria.

References

Spiegel, R., et al. Ann. Neurol. 66(3):419-424(2009)Kang, J., et al. Mitochondrion 8(2):103-108(2008)Lindhurst, M.J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(43):15927-15932(2006)

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$ 277.78
Cat# BP5269b
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