ZCHC4 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9H5U6 |
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Other Accession | NP_079212.2 |
Clone Names | 91201124 |
Gene ID | 29063 |
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Other Names | Zinc finger CCHC domain-containing protein 4, ZCCHC4 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ZCCHC4 {ECO:0000303|PubMed:30531910, ECO:0000312|HGNC:HGNC:22917} |
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Function | rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA (PubMed:30531910, PubMed:31328227, PubMed:31799605, PubMed:31695039). N6-methylation of adenine(4220) in 28S rRNA is required for translation (PubMed:30531910, PubMed:31799605). |
Cellular Location | Nucleus, nucleolus. Cytoplasm Note=Accumulates in the nucleolus, where ribosome biogenesis takes place. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ZCHC4 may be a methyltransferase.
References
Olsen, J.V., et al. Cell 127(3):635-648(2006)Albrecht, M., et al. FEBS Lett. 569 (1-3), 18-26 (2004)
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