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AKNA Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q7Z591
Other Accession NP_110394.3
Clone Names 91208146
Peptide ID 91208146
Additional Information
Gene ID 80709
Other Names AT-hook-containing transcription factor, AKNA, KIAA1968
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKNA
Synonyms KIAA1968
Function Transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. Binds to A/T-rich promoters.
Cellular Location Nucleus.
Tissue Location Predominantly expressed by lymphoid tissues. Highly expressed in the spleen, lymph nodes and peripheral blood leukocytes, expressed at lower level in the thymus. Mainly expressed by germinal center B-lymphocytes, a stage in which receptor and ligand interactions are crucial for B-lymphocyte maturation. Expressed by B- and T-lymphocytes, Natural killer cells and CD1a(+)CD14(-) but not CD1a(-)CD14(+) dendritic cells Weakly or not expressed in fetal liver and in adult bone marrow
Research Areas
Citations (0)

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Background

AKNA transcription factor that specifically activates the expression of the CD40 receptor and its ligand CD40L/CD154, two cell surface molecules on lymphocytes that are critical for antigen-dependent-B-cell development. It binds to A/T-rich promoters.

References

Sims-Mourtada, J.C., et al. DNA Cell Biol. 24(5):325-338(2005)Siddiqa, A., et al. Nature 410(6826):383-387(2001)

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$ 80.00
Cat# BP5317a
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