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SH2D2A Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9NP31
Other Accession NP_003966.2
Clone Names 90805103
Peptide ID 90805103
Additional Information
Gene ID 9047
Other Names SH2 domain-containing protein 2A, SH2 domain-containing adapter protein, T cell-specific adapter protein, TSAd, VEGF receptor-associated protein, SH2D2A, SCAP, TSAD, VRAP
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH2D2A
Function Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in the CD4-p56- LCK-dependent signal transduction pathway. Could also play an important role in normal and pathological angiogenesis. Could be an adapter protein that facilitates and regulates interaction of KDR with effector proteins important to endothelial cell survival and proliferation.
Cellular Location Cytoplasm.
Tissue Location Expression limited to tissues of the immune system and, in particular, activated T-cells. Expressed in peripheral blood leukocytes, thymus and spleen. Much lower expression or undetectable, in brain, placenta, skeletal muscle, prostate, testis, ovary, small intestine, and colon. Expressed at low levels in unstimulated T-cells, but not expressed in normal resting or activated B-cells. According to PubMed:10692392, expression is not restricted to activated T-cells, but strongly expressed in blood cell lineages, the endothelium and other cell and tissue types, such as heart, lung, and liver
Research Areas
Citations (0)

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This protein encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants.


Trynka, G., et al. Gut 58(8):1078-1083(2009)Granum, S., et al. J. Biol. Chem. 283(32):21909-21919(2008)Lorentzen, A.R., et al. J. Neuroimmunol. 197(2):152-158(2008)

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$ 80.00
Cat# BP5330c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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