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C2orf3 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P16383 |
|---|---|
| Other Accession | NP_003194.3 |
| Clone Names | 91102037 |
| Gene ID | 6936 |
|---|---|
| Other Names | GC-rich sequence DNA-binding factor 2, GC-rich sequence DNA-binding factor, Transcription factor 9, TCF-9, GCFC2, C2orf3, GCF, TCF9 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GCFC2 |
|---|---|
| Synonyms | C2orf3, GCF, TCF9 |
| Function | Involved in pre-mRNA splicing through regulating spliceosome C complex formation (PubMed:24304693). May play a role during late- stage splicing events and turnover of excised introns (PubMed:24304693). |
| Cellular Location | Nucleus, nucleoplasm. Nucleus, nucleolus |
| Tissue Location | Widely expressed in tissues and cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The first mRNA transcript isolated for this gene was part of an artificial chimera derived from two distinct gene transcripts and a primer used in the cloning process (see Genbank accession M29204). A positively charged amino terminus present only in the chimera was determined to bind GC-rich DNA, thus mistakenly thought to identify a transcription factor gene.
References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)Anthoni, H., et al. Hum. Mol. Genet. 16(6):667-677(2007)
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