|Other Accession||Q922Y1, Q32KW2, NP_056937.2|
|Other Names||UBX domain-containing protein 1, SAPK substrate protein 1, UBA/UBX 333 kDa protein, UBXN1, SAKS1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 165-178 of HUMAN UBXN1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. Specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ishibashi, T., et al. J. Biochem. 137(5):617-623(2005)
Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005)
McNeill, H., et al. Biochem. J. 384 (PT 2), 391-400 (2004) :
Puente, X.S., et al. Nat. Rev. Genet. 4(7):544-558(2003)
Hoja, M.R., et al. Exp. Cell Res. 259(1):239-246(2000)
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