C102B Blocking Peptide (C-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q68D86 |
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Other Accession | NP_079057.2 |
Gene ID | 79839 |
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Other Names | Coiled-coil domain-containing protein 102B, CCDC102B, C18orf14 |
Target/Specificity | The synthetic peptide sequence is selected from aa 487-500 of HUMAN CCDC102B |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CCDC102B |
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Synonyms | C18orf14 |
Function | During interphase, forms fibers at the proximal ends of centrioles to maintain centrosome cohesion (PubMed:30404835). During mitosis, dissociates from the centrosome following phosphorylation to allow centrosome separation (PubMed:30404835). Contributes to CROCC/rootletin filament formation (PubMed:30404835). |
Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Note=Concentrated at the proximal ends of centrioles where it forms fibers (PubMed:30404835). Centrosomal localization becomes weak when cells enter prophase and is significantly decreased in metaphase (PubMed:30404835). |
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Provided below are standard protocols that you may find useful for product applications.
References
Miller, Y.E., et al. Genomics 8(1):149-154(1990)
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