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METL5 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q9NRN9
Other Accession NP_054887.2
Additional Information
Gene ID 29081
Other Names Methyltransferase-like protein 5, 211-, METTL5
Target/Specificity The synthetic peptide sequence is selected from aa 90-103 of HUMAN METTL5
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name METTL5 {ECO:0000303|PubMed:31328227, ECO:0000312|HGNC:HGNC:25006}
Function Catalytic subunit of a heterodimer with TRMT112, which specifically methylates the 6th position of adenine in position 1832 of 18S rRNA (PubMed:31328227, PubMed:32217665, PubMed:33357433, PubMed:33428944, PubMed:35033535). N6-methylation of adenine(1832) in 18S rRNA resides in the decoding center of 18S rRNA and is required for translation and embryonic stem cells (ESCs) pluripotency and differentiation (PubMed:33357433).
Cellular Location Nucleus. Presynapse. Postsynapse
Tissue Location Expressed from very early development (8 post- conceptual weeks) and expression persists through adulthood in multiple substructures of the brain, including the cerebellar cortex, hippocampus, and striatum.
Research Areas
Citations (0)
citation

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References

Hillier, L.W., et al. Nature 434(7034):724-731(2005)

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$ 277.78
Cat# BP5382c
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