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NICN1 Blocking Peptide (C-term)

Synthetic peptide

     
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Product Information
Primary Accession Q9BSH3
Other Accession NP_115692.1
Additional Information
Other Names Nicolin-1, NPCEDRG, Tubulin polyglutamylase complex subunit 5, PGs5, NICN1
Target/Specificity The synthetic peptide sequence is selected from aa 163-176 of HUMAN NICN1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NICN1
Cellular Location Nucleus.
Tissue Location High expression level is found in brain, testis, liver and kidney. Weak expression in spleen, leukocytes, small intestine and colon. EMBL; AJ299740; CAC82516.1; -; mRNA EMBL; AF538150; AAN52734.1; -; mRNA EMBL; BC005050; AAH05050.1; -; mRNA EMBL; BC050653; AAH50653.1; -; mRNA CCDS; CCDS2798.1; -. [Q9BSH3-1] RefSeq; NP_115692.1; NM_032316.3. [Q9BSH3-1] UniGene; Hs.191460; - ProteinModelPortal; Q9BSH3; - BioGrid; 124003; 9 STRING; 9606.ENSP00000273598; - iPTMnet; Q9BSH3; - PhosphoSitePlus; Q9BSH3; - BioMuta; NICN1; - DMDM; 51701690; - PaxDb; Q9BSH3; - PRIDE; Q9BSH3; - DNASU; 84276; - Ensembl; ENST00000273598; ENSP00000273598; ENSG00000145029. [Q9BSH3-1] Ensembl; ENST00000423832; ENSP00000413115; ENSG00000145029. [Q9BSH3-1] GeneID; 84276; - KEGG; hsa:84276; - UCSC; uc003cwz.2; human. [Q9BSH3-1] CTD; 84276; - DisGeNET; 84276; - GeneCards; NICN1; - HGNC; HGNC:18317; NICN1 HPA; HPA037550; - MIM; 611516; gene neXtProt; NX_Q9BSH3; - OpenTargets; ENSG00000145029; - OpenTargets; ENSG00000283189; - PharmGKB; PA31623; - eggNOG; ENOG410IHPW; Eukaryota eggNOG; ENOG4111GDK; LUCA GeneTree; ENSGT00390000001505; - HOGENOM; HOG000006705; - HOVERGEN; HBG052619; - InParanoid; Q9BSH3; - KO; K16607; - OMA; CDMARVL; - OrthoDB; EOG091G0NXM; - PhylomeDB; Q9BSH3; - TreeFam; TF329753; - BioCyc; ZFISH:ENSG00000145029-MONOMER; - ChiTaRS; NICN1; human GenomeRNAi; 84276; - PRO; PR:Q9BSH3; - Proteomes; UP000005640; Chromosome 3 Bgee; ENSG00000145029; - CleanEx; HS_NICN1; - ExpressionAtlas; Q9BSH3; baseline and differential Genevisible; Q9BSH3; HS GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell 2: Evidence at transcript level; Alternative splicing; Complete proteome; Microtubule; Nucleus; Reference proteome CHAIN 1 213 Nicolin-1 /FTId=PRO_0000096814 VAR_SEQ 166 213 GLPDPSRVSSEVQQMWALTEMIRASHTSARIGRFDVDGCYD LNLLSYT -> VSPHPR (in isoform 2) {ECO:0000303|Ref.2} /FTId=VSP_011420 CONFLICT 45 46 Missing (in Ref. 2; AAN52734) SEQUENCE 213 AA; 24202 MW; 2170A24989952652 CRC64; MSRVLVPCHV KGSVALQVGD VRTSQGRPGV LVIDVTFPSV APFELQEITF KNYYTAFLSI RVRQYTSAHT PAKWVTCLRD YCLMPDPHSE EGAQEYVSLF KHQMLCDMAR ISELRLILRQ PSPLWLSFTV EELQIYQQGP KSPSVTFPKW LSHPVPCEQP ALLREGLPDP SRVSSEVQQM WALTEMIRAS HTSARIGRFD VDGCYDLNLL SYT
Research Areas
Citations (0)

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Background

This protein encoded by this gene localizes to the nucleus and is expressed in numerous tissues including brain, testis, liver, and kidney. This refseq contains genomic sequence in its 3' UTR which is not supported by experimental evidence. Computer predictions indicate that this region of the 3' UTR contains hairpin-forming self-complementary sequence which is possibly excised after transcription. This gene has a pseudogene on chromosome X.

References

Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Backofen, B., et al. Eur. J. Biochem. 269(21):5240-5245(2002)
Backofen, B., et al. DNA Seq. 13(4):179-183(2002)

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