|Other Names||COMM domain-containing protein 8, COMMD8|
|Target/Specificity||The synthetic peptide sequence is selected from aa 60-74 of HUMAN COMMD8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). May down-regulate activation of NF-kappa-B (PubMed:15799966).|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Widely expressed with highest expression in thyroid.|
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Provided below are standard protocols that you may find useful for product applications.
Burstein, E., et al. J. Biol. Chem. 280(23):22222-22232(2005)
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