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RFX7 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q2KHR2 |
|---|---|
| Other Accession | NP_073752.5 |
| Gene ID | 64864 |
|---|---|
| Other Names | DNA-binding protein RFX7, Regulatory factor X 7, Regulatory factor X domain-containing protein 2, RFX7, RFXDC2 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 23-37 of HUMAN RFX7 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RFX7 (HGNC:25777) |
|---|---|
| Synonyms | RFXDC2 |
| Function | Transcription factor (PubMed:29967452). Acts as a transcriptional activator by binding to promoter regions of target genes, such as PDCD4, PIK3IP1, MXD4, PNRC1, and RFX5 (PubMed:29967452, PubMed:34197623). Plays a role in natural killer (NK) cell maintenance and immunity (PubMed:29967452). May play a role in the process of ciliogenesis in the neural tube and neural tube closure (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00858}. |
| Tissue Location | Widely expressed in many different tissue types including thymus and placenta, with high expression in brain (PubMed:18673564). Expressed in both inhibitory and excitatory neurons in cortex (PubMed:33658631). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
RFX7 is a member of the regulatory factor X (RFX) family of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008 [PubMed 18673564]).
References
Crowther-Swanepoel, D., et al. Nat. Genet. 42(2):132-136(2010)
Aftab, S., et al. BMC Evol. Biol. 8, 226 (2008) :
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
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