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C17orf71 Blocking Peptide (N-term)

Synthetic peptide

Product Information
Primary Accession Q8ND04
Other Accession A1A4J7, NP_060619.4
Additional Information
Gene ID 55181
Other Names Protein SMG8, Amplified in breast cancer gene 2 protein, Protein smg-8 homolog, SMG8, ABC2, C17orf71
Target/Specificity The synthetic peptide sequence is selected from aa 276-290 of HUMAN SMG8
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SMG8
Synonyms ABC2, C17orf71
Function Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC). Acts as a regulator of kinase activity.
Research Areas
Citations (0)

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Yamashita, A., et al. Genes Dev. 23(9):1091-1105(2009)

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$ 80.00
$ 99.00
Cat# BP5399a
(40 western blots)
Availability: 2 weeks
Bulk Size
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