FUZ Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BT04 |
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Other Accession | NP_079405.2, NP_001165408.1 |
Gene ID | 80199 |
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Other Names | Protein fuzzy homolog, FUZ, FY |
Target/Specificity | The synthetic peptide sequence is selected from aa 115-129 of HUMAN FUZ |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | FUZ |
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Synonyms | FY |
Function | Probable planar cell polarity effector involved in cilium biogenesis. May regulate protein and membrane transport to the cilium. Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies. May regulate the morphogenesis of hair follicles which depends on functional primary cilia (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q2HZX7}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q2HZX7}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:Q3UYI6} |
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Provided below are standard protocols that you may find useful for product applications.
References
Park, T.J., et al. Nat. Genet. 38(3):303-311(2006)
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