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C19orf29 Blocking Peptide (N-term)
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8WUQ7 |
|---|---|
| Other Accession | Q9CS00, NP_067054.1 |
| Gene ID | 58509 |
|---|---|
| Other Names | Cactin, Renal carcinoma antigen NY-REN-24, CACTIN, C19orf29 |
| Target/Specificity | The synthetic peptide sequence is selected from aa 227-240 of HUMAN CACTIN |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CACTIN |
|---|---|
| Synonyms | C19orf29 |
| Function | Plays a role in pre-mRNA splicing by facilitating excision of a subset of introns (PubMed:28062851). Required for the splicing of CDCA5/Sororin, a regulator of sister chromatid cohesion (PubMed:28062851). Involved in the regulation of innate immune response (PubMed:20829348). Acts as a negative regulator of Toll-like receptor, interferon-regulatory factor (IRF) and canonical NF-kappa-B signaling pathways (PubMed:20829348, PubMed:26363554). Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous pro-inflammatory stimuli (PubMed:20829348, PubMed:26363554). |
| Cellular Location | Nucleus. Cytoplasm, cytosol. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Sogayar, M.C., et al. Genome Res. 14(7):1413-1423(2004)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Lehner, B., et al. Genomics 83(1):153-167(2004)
Jurica, M.S., et al. RNA 8(4):426-439(2002)
Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999)
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