|Other Accession||Q9CS00, NP_067054.1|
|Other Names||Cactin, Renal carcinoma antigen NY-REN-24, CACTIN, C19orf29|
|Target/Specificity||The synthetic peptide sequence is selected from aa 227-240 of HUMAN CACTIN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing.|
|Cellular Location||Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Sogayar, M.C., et al. Genome Res. 14(7):1413-1423(2004)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Lehner, B., et al. Genomics 83(1):153-167(2004)
Jurica, M.S., et al. RNA 8(4):426-439(2002)
Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999)
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