|Other Accession||Q9CS00, NP_067054.1|
|Other Names||Cactin, Renal carcinoma antigen NY-REN-24, CACTIN, C19orf29|
|Target/Specificity||The synthetic peptide sequence is selected from aa 227-240 of HUMAN CACTIN|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing.|
|Cellular Location||Nucleus. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus|
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Provided below are standard protocols that you may find useful for product applications.
Beausoleil, S.A., et al. Proc. Natl. Acad. Sci. U.S.A. 101(33):12130-12135(2004)
Sogayar, M.C., et al. Genome Res. 14(7):1413-1423(2004)
Grimwood, J., et al. Nature 428(6982):529-535(2004)
Lehner, B., et al. Genomics 83(1):153-167(2004)
Jurica, M.S., et al. RNA 8(4):426-439(2002)
Scanlan, M.J., et al. Int. J. Cancer 83(4):456-464(1999)
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