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CD69 Blocking Peptide (Center)

Synthetic peptide

     
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Product Information
Primary Accession Q07108
Other Accession NP_001772.1
Additional Information
Gene ID 969
Other Names Early activation antigen CD69, Activation inducer molecule, AIM, BL-AC/P26, C-type lectin domain family 2 member C, EA1, Early T-cell activation antigen p60, GP32/28, Leukocyte surface antigen Leu-23, MLR-3, CD69, CD69, CLEC2C
Target/Specificity The synthetic peptide sequence is selected from aa 134-148 of HUMAN CD69
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD69
Synonyms CLEC2C
Function Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
Cellular Location Membrane; Single-pass type II membrane protein.
Tissue Location Expressed on the surface of activated T-cells, B- cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets
Research Areas
Citations (0)
citation

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Background

This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. Alternative splicing results in multiple transcript variants.

References

Davila, S., et al. Genes Immun. (2010) In press :
Kolenko, P., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 65 (PT 12), 1258-1260 (2009) :
Hu, M., et al. J. Mol. Recognit. 22(6):516-520(2009)
Radstake, T.R., et al. PLoS ONE 4 (6), E5981 (2009) :
Natarajan, K., et al. Biochemistry 39(48):14779-14786(2000)
Vance, B.A., et al. Arch. Biochem. Biophys. 368(2):214-220(1999)
Lopez-Cabrera, M., et al. J. Biol. Chem. 270(37):21545-21551(1995)
Bezouska, K., et al. Biochem. Biophys. Res. Commun. 208(1):68-74(1995)
Santis, A.G., et al. Eur. J. Immunol. 24(7):1692-1697(1994)
Lopez-Cabrera, M., et al. J. Exp. Med. 178(2):537-547(1993)
Ziegler, S.F., et al. Eur. J. Immunol. 23(7):1643-1648(1993)
Cambiaggi, C., et al. Immunogenetics 36(2):117-120(1992)

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$ 277.78
Cat# BP5413c
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