|Other Accession||Q5U2V5, Q80ZM8, NP_001120930.1, NP_061968.1|
|Other Names||Cardiolipin synthase, CLS, 278-, Protein GCD10 homolog, CRLS1, C20orf155, CLS1|
|Target/Specificity||The synthetic peptide sequence is selected from aa 213-226 of HUMAN CRLS1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
|Tissue Location||Highly expressed in tissues such as heart, skeletal muscle and liver.|
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Provided below are standard protocols that you may find useful for product applications.
Garcia-Carrasco, M., et al. Clin Rev Allergy Immunol 36 (2-3), 104-108 (2009) :
Lee, J.L., et al. Clin Rev Allergy Immunol 36 (2-3), 126-130 (2009) :
Stojanovich, L., et al. Clin Rev Allergy Immunol 36 (2-3), 74-79 (2009) :
Miesbach, W. Clin Rev Allergy Immunol 36 (2-3), 91-97 (2009) :
Chen, D., et al. Biochem. J. 398(2):169-176(2006)
Lu, B., et al. J. Lipid Res. 47(6):1140-1145(2006)
Houtkooper, R.H., et al. FEBS Lett. 580(13):3059-3064(2006)
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Johnson, E.M., et al. Nucleic Acids Res. 31(11):2915-2925(2003)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
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