DAAM1-T361 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y4D1 |
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Other Accession | NP_055807.1 |
Clone Names | 80130182 |
Gene ID | 23002 |
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Other Names | Disheveled-associated activator of morphogenesis 1, DAAM1, KIAA0666 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DAAM1 |
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Synonyms | KIAA0666 |
Function | Binds to disheveled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex formation. May play a role as a scaffolding protein to recruit Rho-GDP and Rho-GEF, thereby enhancing Rho-GTP formation. Can direct nucleation and elongation of new actin filaments. Involved in building functional cilia (PubMed:16630611, PubMed:17482208). Involved in the organization of the subapical actin network in multiciliated epithelial cells (By similarity). Together with DAAM2, required for myocardial maturation and sarcomere assembly (By similarity). |
Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Perinuclear |
Tissue Location | Expressed in all tissues examined. |
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