|Other Names||Transportin-3, Importin-12, Imp12, Transportin-SR, TRN-SR, TNPO3, IPO12|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains.|
|Cellular Location||Cytoplasm. Nucleus|
|Tissue Location||Expressed in skeletal muscle.|
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Provided below are standard protocols that you may find useful for product applications.
TNPO3 is a nuclear import receptor forserine/arginine-rich (SR) proteins, which are essentialprecursor-mRNA splicing factors.
Krishnan, L., et al. J. Virol. 84(1):397-406(2010)Hirschfield, G.M., et al. N. Engl. J. Med. 360(24):2544-2555(2009)Ito, I., et al. Arthritis Rheum. 60(6):1845-1850(2009)
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