|Other Names||ATPase SWSAP1, SWIM-type zinc finger 7-associated protein 1, SWS1-associated protein 1, ZSWIM7-associated protein 1, ZSWIM7AP1, SWSAP1, C19orf39|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||ATPase which is preferentially stimulated by single- stranded DNA and is involved in homologous recombination repair (HRR). Has a DNA-binding activity which is independent of its ATPase activity.|
|Cellular Location||Nucleus. EMBL; AK092438; BAC03891.1; -; mRNA EMBL; AC024575; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC068071; AAH68071.1; -; mRNA EMBL; BC119677; AAI19678.1; -; mRNA CCDS; CCDS12259.1; - RefSeq; NP_787067.2; NM_175871.3 UniGene; Hs.631619; - ProteinModelPortal; Q6NVH7; - BioGrid; 125954; 10 IntAct; Q6NVH7; 6 STRING; 9606.ENSP00000310008; - iPTMnet; Q6NVH7; - PhosphoSitePlus; Q6NVH7; - BioMuta; SWSAP1; - DMDM; 74736850; - EPD; Q6NVH7; - MaxQB; Q6NVH7; - PaxDb; Q6NVH7; - PeptideAtlas; Q6NVH7; - PRIDE; Q6NVH7; - Ensembl; ENST00000312423; ENSP00000310008; ENSG00000173928 GeneID; 126074; - KEGG; hsa:126074; - UCSC; uc002mrg.2; human CTD; 126074; - GeneCards; SWSAP1; - HGNC; HGNC:26638; SWSAP1 HPA; HPA052712; - MIM; 614536; gene neXtProt; NX_Q6NVH7; - OpenTargets; ENSG00000173928; - PharmGKB; PA144596472; - eggNOG; ENOG410IGP0; Eukaryota eggNOG; ENOG41128AG; LUCA GeneTree; ENSGT00390000007170; - HOGENOM; HOG000001573; - HOVERGEN; HBG094964; - InParanoid; Q6NVH7; - OMA; PMRLQKI; - OrthoDB; EOG091G0F7H; - PhylomeDB; Q6NVH7; - TreeFam; TF337313; - GenomeRNAi; 126074; - PRO; PR:Q6NVH7; - Proteomes; UP000005640; Chromosome 19 Bgee; ENSG00000173928; - CleanEx; HS_C19orf39; - Genevisible; Q6NVH7; HS GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0097196; C:Shu complex; IDA:UniProtKB GO; GO:0016887; F:ATPase activity; IDA:UniProtKB GO; GO:0003697; F:single-stranded DNA binding; IDA:UniProtKB GO; GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB GO; GO:0050821; P:protein stabilization; IMP:UniProtKB Gene3D; 188.8.131.520; -; 1 InterPro; IPR027417; P-loop_NTPase InterPro; IPR033586; SWSAP1 PANTHER; PTHR28653; PTHR28653; 1 SUPFAM; SSF52540; SSF52540; 1 1: Evidence at protein level; Complete proteome; DNA damage; DNA recombination; DNA repair; DNA-binding; Nucleus; Polymorphism; Reference proteome CHAIN 1 229 ATPase SWSAP1 /FTId=PRO_0000294240 VARIANT 171 171 D -> G (in dbSNP:rs317926) /FTId=VAR_033151 MUTAGEN 18 18 K->A: Loss of function in HRR associated with altered ssDNA-stimulated ATPase activity. MUTAGEN 96 96 D->A: Loss of function in HRR associated with altered ssDNA-stimulated ATPase activity. CONFLICT 113 113 Y -> C (in Ref. 1; BAC03891) SEQUENCE 229 AA; 24311 MW; AB940178B7A4A6C6 CRC64; MPAAGPPLLL LGTPGSGKTA LLFAAALEAA GEGQGPVLFL TRRPLQSMPR GTGTTLDPMR LQKIRFQYPP STRELFRLLC SAHEAPGPAP SLLLLDGLEE YLAEDPEPQE AAYLIALLLD TAAHFSHRLG PGRDCGLMVA LQTQEEAGSG DVLHLALLQR YFPAQCWLQP DAPGPGEHGL RACLEPGGLG PRTEWWVTFR SDGEMMIAPW PTQAGDPSSG KGSSSGGQP|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.