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AVP Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P01185
Other Accession NP_000481.2
Clone Names 90826049
Additional Information
Gene ID 551
Other Names Vasopressin-neurophysin 2-copeptin, AVP-NPII, Arg-vasopressin, Arginine-vasopressin, Neurophysin 2, Neurophysin-II, Copeptin, AVP, ARVP, VP
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name AVP
Synonyms ARVP, VP
Function [Neurophysin 2]: Specifically binds vasopressin.
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

This gene encodes a precursor protein consisting ofarginine vasopressin and two associated proteins, neurophysin 2 anda glycopeptide, copeptin. Arginine vasopressin is a posteriorpituitary hormone which is synthesized in the supraoptic nucleusand paraventricular nucleus of the hypothalamus. Along with itscarrier protein, neurophysin 2, it is packaged into neurosecretoryvesicles and transported axonally to the nerve endings in theneurohypophysis where it is either stored or secreted into thebloodstream. The precursor is thought to be activated while it isbeing transported along the axon to the posterior pituitary.Arginine vasopressin acts as a growth factor by enhancing pHregulation through acid-base transport systems. It has a directantidiuretic action on the kidney, and also causes vasoconstrictionof the peripheral vessels. This hormone can contract smooth muscleduring parturition and lactation. It is also involved in cognition,tolerance, adaptation and complex sexual and maternal behaviour, aswell as in the regulation of water excretion and cardiovascularfunctions.

References

Abu Libdeh, A., et al. Eur. J. Endocrinol. 162(2):221-226(2010)Cirillo, M. Kidney Int. 77(1):5-6(2010)Meijer, E., et al. Kidney Int. 77(1):29-36(2010)Birk, J., et al. J. Cell. Sci. 122 (PT 21), 3994-4002 (2009)

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$ 277.78
Cat# BP5558c
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Availability: 2 weeks
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