|Other Names||Tetraspanin-3, Tspan-3, Tetraspanin TM4-A, Transmembrane 4 superfamily member 8, TSPAN3, TM4SF8|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene is a member of thetransmembrane 4 superfamily, also known as the tetraspanin family.Most of these members are cell-surface proteins that arecharacterized by the presence of four hydrophobic domains. Theproteins mediate signal transduction events that play a role in theregulation of cell development, activation, growth and motility.The use of alternate polyadenylation sites has been found for thisgene.
Berditchevski, F. J. Cell. Sci. 114 (PT 23), 4143-4151 (2001) :Todd, S.C., et al. Biochim. Biophys. Acta 1399(1):101-104(1998)Wu, Y.J., et al. J. Biol. Chem. 266(26):17566-17572(1991)
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