|Other Names||Mitochondrial ornithine transporter 1, Solute carrier family 25 member 15, SLC25A15, ORNT1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Ornithine transport across inner mitochondrial membrane, from the cytoplasm to the matrix.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
This gene is a member of the mitochondrial carrier family.The encoded protein transports ornithine across the innermitochondrial membrane from the cytosol to the mitochondrialmatrix. The protein is an essential component of the urea cycle,and functions in ammonium detoxification and biosynthesis of theamino acid arginine. Mutations in this gene result inhyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome.There is a pseudogene of this locus on the Y chromosome.
Salvi, S., et al. Hum. Mutat. 18 (5), 460 (2001) Salvi, S., et al. Neurology 57(5):911-914(2001)Miyamoto, T., et al. J. Hum. Genet. 46(5):260-262(2001)Tsujino, S., et al. Ann. Neurol. 47(5):625-631(2000)Camacho, J.A., et al. Nat. Genet. 22(2):151-158(1999)
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