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SMCR7L Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9NQG6
Other Accession NP_061881.2
Clone Names 91102301
Peptide ID 91102301
Additional Information
Gene ID 54471
Other Names Mitochondrial dynamics protein MID51, Mitochondrial dynamics protein of 51 kDa, Mitochondrial elongation factor 1, Smith-Magenis syndrome chromosomal region candidate gene 7 protein-like, SMCR7-like protein, MIEF1, MID51, SMCR7L
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MIEF1
Synonyms MID51, SMCR7L
Function Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.
Cellular Location Mitochondrion outer membrane; Single-pass membrane protein
Tissue Location Expression is relatively high in heart, skeletal muscle, pancreas and kidney
Research Areas
Citations (0)

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SMCR7L belongs to the SMCR7 family. The specific function of this protein remains unknown.


Jin, J., et al. Curr. Biol. 14(16):1436-1450(2004)Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)Dunham, I., et al. Nature 402(6761):489-495(1999)

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$ 80.00
Cat# BP5571a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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