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GT251 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NBJ5 |
|---|---|
| Other Accession | NP_078932.2 |
| Clone Names | 91109133 |
| Gene ID | 79709 |
|---|---|
| Other Names | Procollagen galactosyltransferase 1, Collagen beta(1-O)galactosyltransferase 1, Glycosyltransferase 25 family member 1, Hydroxylysine galactosyltransferase 1, COLGALT1, GLT25D1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | COLGALT1 |
|---|---|
| Synonyms | GLT25D1 |
| Function | Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of type I collagen (PubMed:19075007, PubMed:22216269, PubMed:27402836). By acting on collagen glycosylation, facilitates the formation of collagen triple helix (PubMed:27402836). Also involved in the biosynthesis of collagen type IV (PubMed:30412317). |
| Cellular Location | Endoplasmic reticulum lumen {ECO:0000255|PROSITE- ProRule:PRU10138, ECO:0000269|PubMed:20470363}. Note=Colocalized with PLOD3 and mannose binding lectin/MBL2. |
| Tissue Location | Ubiquitous with higher levels in placenta, heart, lung and spleen. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
GLT25D1 has a beta-galactosyltransferase activity; transfers beta-galactose to hydroxylysine residues of collagen.
References
Schegg, B., et al. Mol. Cell. Biol. 29(4):943-952(2009)
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