CALL5 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9NZT1 |
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Other Accession | NP_059118.2 |
Clone Names | 91109157 |
Gene ID | 51806 |
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Other Names | Calmodulin-like protein 5, Calmodulin-like skin protein, CALML5, CLSP |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CALML5 |
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Synonyms | CLSP |
Function | Binds calcium. May be involved in terminal differentiation of keratinocytes. |
Tissue Location | Particularly abundant in the epidermis where its expression is directly related to keratinocyte differentiation. Very low expression in lung |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a novel calcium binding proteinexpressed in the epidermis and related to the calmodulin family ofcalcium binding proteins. Functional studies with recombinantprotein demonstrate it does bind calcium and undergoes aconformational change when it does so. Abundant expression isdetected only in reconstructed epidermis and is restricted todifferentiating keratinocytes. In addition, it can associate withtransglutaminase 3, shown to be a key enzyme in the terminaldifferentiation of keratinocytes.
References
Durussel, I., et al. Biochemistry 41(17):5439-5448(2002)Mehul, B., et al. J. Invest. Dermatol. 116(6):905-909(2001)Mehul, B., et al. J. Biol. Chem. 275(17):12841-12847(2000)
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