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RT28 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q9Y2Q9
Other Accession NP_054737.1
Clone Names 91109260
Peptide ID 91109260
Additional Information
Other Names 28S ribosomal protein S28, mitochondrial, MRP-S28, S28mt, 28S ribosomal protein S35, mitochondrial, MRP-S35, S35mt, MRPS28, MRPS35
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MRPS28
Synonyms MRPS35
Cellular Location Mitochondrion. EMBL; AF070663; AAD20969.1; -; mRNA EMBL; AK315739; BAG38094.1; -; mRNA EMBL; CH471068; EAW87069.1; -; Genomic_DNA EMBL; BC010150; AAH10150.1; -; mRNA EMBL; AB061209; BAB54959.1; -; Genomic_DNA CCDS; CCDS6226.1; - RefSeq; NP_054737.1; NM_014018.2 UniGene; Hs.521124; - PDB; 3J9M; EM; 3.50 A; AW=1-187 PDBsum; 3J9M; - ProteinModelPortal; Q9Y2Q9; - SMR; Q9Y2Q9; - BioGrid; 118784; 52 IntAct; Q9Y2Q9; 8 MINT; MINT-8052210; - STRING; 9606.ENSP00000276585; - iPTMnet; Q9Y2Q9; - PhosphoSitePlus; Q9Y2Q9; - BioMuta; MRPS28; - DMDM; 22001973; - EPD; Q9Y2Q9; - MaxQB; Q9Y2Q9; - PaxDb; Q9Y2Q9; - PeptideAtlas; Q9Y2Q9; - PRIDE; Q9Y2Q9; - TopDownProteomics; Q9Y2Q9; - DNASU; 28957; - Ensembl; ENST00000276585; ENSP00000276585; ENSG00000147586 GeneID; 28957; - KEGG; hsa:28957; - UCSC; uc003ybp.4; human CTD; 28957; - DisGeNET; 28957; - GeneCards; MRPS28; - HGNC; HGNC:14513; MRPS28 HPA; HPA027202; - MIM; 611990; gene neXtProt; NX_Q9Y2Q9; - OpenTargets; ENSG00000147586; - PharmGKB; PA31016; - eggNOG; KOG4078; Eukaryota eggNOG; ENOG4111RYH; LUCA GeneTree; ENSGT00390000001057; - HOGENOM; HOG000230806; - HOVERGEN; HBG036126; - InParanoid; Q9Y2Q9; - KO; K17407; - OMA; CRTRAVT; - OrthoDB; EOG091G0VHY; - PhylomeDB; Q9Y2Q9; - TreeFam; TF315097; - BioCyc; ZFISH:ENSG00000147586-MONOMER; - Reactome; R-HSA-5368286; Mitochondrial translation initiation Reactome; R-HSA-5389840; Mitochondrial translation elongation Reactome; R-HSA-5419276; Mitochondrial translation termination ChiTaRS; MRPS28; human GeneWiki; MRPS28; - GenomeRNAi; 28957; - PRO; PR:Q9Y2Q9; - Proteomes; UP000005640; Chromosome 8 Bgee; ENSG00000147586; - CleanEx; HS_MRPS28; - CleanEx; HS_MRPS35; - ExpressionAtlas; Q9Y2Q9; baseline and differential Genevisible; Q9Y2Q9; HS GO; GO:0005743; C:mitochondrial inner membrane; TAS:Reactome GO; GO:0005763; C:mitochondrial small ribosomal subunit; TAS:UniProtKB GO; GO:0005739; C:mitochondrion; IDA:HPA GO; GO:0044822; F:poly(A) RNA binding; IDA:UniProtKB GO; GO:0070125; P:mitochondrial translational elongation; TAS:Reactome GO; GO:0070126; P:mitochondrial translational termination; TAS:Reactome InterPro; IPR019375; Ribosomal_S28_mit Pfam; PF10246; MRP-S35; 1 1: Evidence at protein level; 3D-structure; Acetylation; Complete proteome; Mitochondrion; Phosphoprotein; Polymorphism; Reference proteome; Ribonucleoprotein; Ribosomal protein; Transit peptide TRANSIT 1 71 Mitochondrion. CHAIN 72 187 28S ribosomal protein S28, mitochondrial /FTId=PRO_0000087714 MOD_RES 73 73 Phosphoserine {ECO:0000250|UniProtKB:Q9CY16} MOD_RES 133 133 N6-acetyllysine VARIANT 103 103 R -> W (in dbSNP:rs16919579) /FTId=VAR_052047 SEQUENCE 187 AA; 20843 MW; 2ED0EA43552B9B54 CRC64; MAALCRTRAV AAESHFLRVF LFFRPFRGVG TESGSESGSS NAKEPKTRAG GFASALERHS ELLQKVEPLQ KGSPKNVESF ASMLRHSPLT QMGPAKDKLV IGRIFHIVEN DLYIDFGGKF HCVCRRPEVD GEKYQKGTRV RLRLLDLELT SRFLGATTDT TVLEANAVLL GIQESKDSRS KEEHHEK
Research Areas
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Background

Mammalian mitochondrial ribosomal proteins are encoded bynuclear genes and help in protein synthesis within themitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of asmall 28S subunit and a large 39S subunit. They have an estimated75% protein to rRNA composition compared to prokaryotic ribosomes,where this ratio is reversed. Another difference between mammalianmitoribosomes and prokaryotic ribosomes is that the latter containa 5S rRNA. Among different species, the proteins comprising themitoribosome differ greatly in sequence, and sometimes inbiochemical properties, which prevents easy recognition by sequencehomology. This gene encodes a 28S subunit protein that has beencalled mitochondrial ribosomal protein S35 in the literature.

References

Zhang, Z., et al. Genomics 81(5):468-480(2003)Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :Cavdar Koc, E., et al. J. Biol. Chem. 276(22):19363-19374(2001)Koc, E.C., et al. J. Biol. Chem. 275(42):32585-32591(2000)O'Brien, T.W., et al. J. Biol. Chem. 275(24):18153-18159(2000)

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$ 80.00
Cat# BP5587b
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