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ZFP90 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TF47 |
|---|---|
| Other Accession | NP_597715.2 |
| Clone Names | 91119294 |
| Gene ID | 146198 |
|---|---|
| Other Names | Zinc finger protein 90 homolog, Zfp-90, Zinc finger protein 756, ZFP90, KIAA1954, ZNF756 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ZFP90 |
|---|---|
| Synonyms | KIAA1954, ZNF756 |
| Function | Inhibits the transcriptional repressor activity of REST by inhibiting its binding to DNA, thereby derepressing transcription of REST target genes. |
| Cellular Location | Nucleus {ECO:0000250|UniProtKB:Q61967}. Note=Colocalizes with REST in the nucleus {ECO:0000250|UniProtKB:Q61967} |
| Tissue Location | Expressed in heart (PubMed:21284946). Isoform 2: Highly expressed in regulatory T-cells (Treg) (PubMed:23543754) |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
ZFP90 may function as a repressor or silencer protein, and most likely exerts its repressing activity upon zinc dependent binding to DNA. It may be involved in proper spermatogenesis by repressing the expression of genes unnecessary or incompatible with the maintenance of a haploid cell state.
References
Barrett, J.C., et al. Nat. Genet. 41(12):1330-1334(2009)Macedo-Souza, L.I., et al. Ann. Neurol. 57(5):730-737(2005)Lange, R., et al. DNA Cell Biol. 14(11):971-981(1995)
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