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IQUB Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NA54 |
|---|---|
| Other Accession | NP_849149.3 |
| Clone Names | 91216060 |
| Gene ID | 154865 |
|---|---|
| Other Names | IQ and ubiquitin-like domain-containing protein, IQUB |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | IQUB |
|---|---|
| Function | Adapter protein that anchors the radial spoke 1 (RS1) complex to the A microtubule of outer doublet microtubules in axonemes (PubMed:36355624). The triple radial spokes (RS1, RS2 and RS3) are required to modulate beating of the sperm flagellum (PubMed:36355624). May play a role in inhibiting signaling via MAPK1/ERK2 and MAPK3/ERK1 (PubMed:36355624). Additionally, may play a role in the functioning of cilia (By similarity). Not required for the functioning of tracheal or ependymal cilia (By similarity). |
| Cellular Location | Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q8CDK3}. Cell projection, cilium {ECO:0000250|UniProtKB:Q8CDK3}. Note=Localizes to the axoneme of sperm cells and the cilia of tracheal epithelial cells {ECO:0000250|UniProtKB:Q8CDK3} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Kimura, K., et al. Genome Res. 16(1):55-65(2006)Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
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