|Other Names||Muscle-related coiled-coil protein, Muscle-restricted coiled-coil protein, MURC|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.|
|Cellular Location||Cytoplasm, myofibril, sarcomere. Cytoplasm. Note=In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
MURC induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway.
Tagawa, M., et al. Am. J. Physiol., Cell Physiol. 295 (2), C490-C498 (2008) :Ogata, T., et al. Mol. Cell. Biol. 28(10):3424-3436(2008)
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