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IKZF3 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9UKT9
Other Accession NP_036613.2
Clone Names 91023117
Peptide ID 91023117
Additional Information
Gene ID 22806
Other Names Zinc finger protein Aiolos, Ikaros family zinc finger protein 3, IKZF3, ZNFN1A3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name IKZF3
Synonyms ZNFN1A3
Function Transcription factor that plays an important role in the regulation of lymphocyte differentiation. Plays an essential role in regulation of B-cell differentiation, proliferation and maturation to an effector state. Involved in regulating BCL2 expression and controlling apoptosis in T-cells in an IL2- dependent manner.
Cellular Location Nucleus. Cytoplasm.
Tissue Location Expressed most strongly in peripheral blood leukocytes, the spleen, and the thymus
Research Areas
Citations (0)

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This gene encodes a member of the Ikaros family ofzinc-finger proteins. Three members of this protein family (Ikaros,Aiolos and Helios) are hematopoietic-specific transcription factorsinvolved in the regulation of lymphocyte development. This geneproduct is a transcription factor that is important in theregulation of B lymphocyte proliferation and differentiation. BothIkaros and Aiolos can participate in chromatin remodeling.Regulation of gene expression in B lymphocytes by Aiolos is complexas it appears to require the sequential formation of Ikaroshomodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Atleast six alternative transcripts encoding different isoforms havebeen described.


Billot, K., et al. Leuk. Res. 34(3):289-293(2010)Hirschfield, G.M., et al. N. Engl. J. Med. 360(24):2544-2555(2009)Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)

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$ 80.00
Cat# BP5656c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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