|Other Names||Butyrophilin-like protein 2, BTL-II, BTNL2|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Negative regulator of T-cell proliferation.|
|Cellular Location||Membrane; Single-pass type II membrane protein. Note=Isoform 2 is present in the nuclear, vesicle and plasma membranes, isoform 3 is found in cytoplasmic vesicle structures and is not membrane bound|
|Tissue Location||Expressed in brain, heart, kidney, liver, pancreas, ovary, leukocyte, small intestine, testis and thymus|
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Provided below are standard protocols that you may find useful for product applications.
LIM domain only 3 (LMO3) belongs to the rhombotin family of cysteine-rich LIM domain oncogenes. It is transcribed mainly in the brain. It interacts with the neuronal transcription factor, HEN2, and acts as an oncogene in neuroblastoma.
Valentonyte, R., et al. Nat. Genet. 37(4):357-364(2005)Hiller, M., et al. Nat. Genet. 36(12):1255-1257(2004)Stammers, M., et al. Immunogenetics 51 (4-5), 373-382 (2000)
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