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GALNT7 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q86SF2 |
|---|---|
| Other Accession | NP_059119.2 |
| Clone Names | 91009161 |
| Gene ID | 51809 |
|---|---|
| Other Names | N-acetylgalactosaminyltransferase 7, 241-, Polypeptide GalNAc transferase 7, GalNAc-T7, pp-GaNTase 7, Protein-UDP acetylgalactosaminyltransferase 7, UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 7, GALNT7 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | GALNT7 |
|---|---|
| Function | Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide substrate may remain unidentified. |
| Cellular Location | Golgi apparatus membrane; Single- pass type II membrane protein |
| Tissue Location | Widely expressed. Expressed in uterus, retina, kidney, small intestine, omentum, stomach and CNS |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
GALNT7 is GalNAc transferase 7, a member of theGalNAc-transferase family. The enzyme encoded by this gene controlsthe initiation step of mucin-type O-linked protein glycosylationand transfer of N-acetylgalactosamine to serine and threonine aminoacid residues. This enzyme is a type II transmembrane protein andshares common sequence motifs with other family members. Unlikeother family members, this enzyme shows exclusive specificity forpartially GalNAc-glycosylated acceptor substrates and shows noactivity with non-glycosylated peptides. This protein may functionas a follow-up enzyme in the initiation step of O-glycosylation.
References
Kahai, S., et al. PLoS ONE 4 (10), E7535 (2009) :Bennett, E.P., et al. FEBS Lett. 460(2):226-230(1999)
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