|Other Names||Rho guanine nucleotide exchange factor 10-like protein, GrinchGEF, ARHGEF10L, GRINCHGEF, KIAA1626|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC.|
|Tissue Location||Detected in heart, liver, skeletal muscle, kidney and pancreas.|
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Provided below are standard protocols that you may find useful for product applications.
ARHGEF10L is a member of the RhoGEF family of guaninenucleotide exchange factors (GEFs) that activate Rho GTPases(Winkler et al., 2005 [PubMed 16112081]).
Takefuji, M., et al. J. Hum. Genet. 55(1):42-49(2010)Stacey, S.N., et al. Nat. Genet. 40(11):1313-1318(2008)Winkler, S., et al. Biochem. Biophys. Res. Commun. 335(4):1280-1286(2005)
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