TDIF2 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q5QJE6 |
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Other Accession | NP_055412.2 |
Clone Names | 91109251 |
Gene ID | 30836 |
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Other Names | Deoxynucleotidyltransferase terminal-interacting protein 2, Estrogen receptor-binding protein, LPTS-interacting protein 2, LPTS-RP2, Terminal deoxynucleotidyltransferase-interacting factor 2, TdIF2, TdT-interacting factor 2, DNTTIP2, ERBP, TDIF2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | DNTTIP2 (HGNC:24013) |
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Synonyms | ERBP, TDIF2 |
Function | Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein (PubMed:12786946, PubMed:15047147). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797). |
Cellular Location | Nucleus. Nucleus, nucleolus |
Tissue Location | Widely expressed with higher levels in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
DNTTIP2 regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein.
References
Fujita, K., et al. Genes Cells 8(6):559-571(2003)Lim, H.D. J Prosthet Dent 67(4):572-573(1992)Soares-da-Silva, P., et al. Br. J. Pharmacol. 105(4):811-816(1992)
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