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TCF4 Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P15884
Other Accession NP_003190.1
Clone Names 90625232
Peptide ID 90625232
Additional Information
Gene ID 6925
Other Names Transcription factor 4, TCF-4, Class B basic helix-loop-helix protein 19, bHLHb19, Immunoglobulin transcription factor 2, ITF-2, SL3-3 enhancer factor 2, SEF-2, TCF4, BHLHB19, ITF2, SEF2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TCF4
Synonyms BHLHB19, ITF2, SEF2
Function Transcription factor that binds to the immunoglobulin enchancer Mu-E5/KE5-motif. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Binds to the E-box present in the somatostatin receptor 2 initiator element (SSTR2-INR) to activate transcription (By similarity). Preferentially binds to either 5'-ACANNTGT-3' or 5'-CCANNTGG-3'.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00981, ECO:0000269|PubMed:22777675}
Tissue Location Expressed in adult heart, brain, placenta, skeletal muscle and to a lesser extent in the lung. In developing embryonic tissues, expression mostly occurs in the brain
Research Areas
Citations (0)

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TCF4 is transcription factor 4, a basichelix-turn-helix transcription factor. The encoded proteinrecognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - amotif first identified in immunoglobulin enhancers. This gene isexpressed predominantly in pre-B-cells, although it is found inother tissues as well. Defects in this gene are a cause ofPitt-Hopkins syndrome.


Rosenfeld, J.A., et al. Genet. Med. 11(11):797-805(2009)Herbst, A., et al. Biochem. Biophys. Res. Commun. 387(4):736-740(2009)Rena, V., et al. Placenta 30(10):876-883(2009)Henthorn, P., et al. Science 247(4941):467-470(1990)

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$ 80.00
Cat# BP5756a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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