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KIRREL Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96J84
Other Accession NP_060710.3
Clone Names 90723073
Peptide ID 90723073
Additional Information
Gene ID 55243
Other Names Kin of IRRE-like protein 1, Kin of irregular chiasm-like protein 1, Nephrin-like protein 1, KIRREL, KIRREL1, NEPH1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIRREL1, NEPH1
Function Plays a significant role in the normal development and function of the glomerular permeability. Signaling protein that needs the presence of TEC kinases to fully trans-activate the transcription factor AP-1 (By similarity).
Cellular Location Cell membrane; Single-pass type I membrane protein. Note=Predominantly located at podocyte slit diaphragm
Tissue Location Abundantly expressed in kidney. Specifically expressed in podocytes of kidney glomeruli
Research Areas
Citations (0)

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NEPH1 is a member of the nephrin-like protein family,which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). Thecytoplasmic domains of these proteins interact with the C terminusof podocin (NPHS2; MIM 604766), and the genes are expressed inkidney podocytes, cells involved in ensuring size- andcharge-selective ultrafiltration (Sellin et al., 2003 [PubMed12424224]).


Huber, T.B., et al. J. Biol. Chem. 278(15):13417-13421(2003)Gerke, P., et al. J. Am. Soc. Nephrol. 14(4):918-926(2003)Sellin, L., et al. FASEB J. 17(1):115-117(2003)Donoviel, D.B., et al. Mol. Cell. Biol. 21(14):4829-4836(2001)

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$ 80.00
Cat# BP5761c
(40 western blots)
Availability: In Stock
Bulk Size
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