|Other Names||Large subunit GTPase 1 homolog, hLsg1, 361-, LSG1|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).|
|Cellular Location||Cytoplasm. Endoplasmic reticulum. Nucleus, Cajal body. Note=Shuttles between the Cajal bodies in the nucleus and the endoplasmic reticulum|
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Provided below are standard protocols that you may find useful for product applications.
LSG1 is a protein related to the yeast largesubunit GTPase 1. The encoded protein is necessary for cellviability and may localize in the endoplasmic reticulum, nucleusand cytoplasm.
Kimura, K., et al. Genome Res. 16(1):55-65(2006)Reynaud, E.G., et al. BMC Biol. 3, 21 (2005) :Dias Neto, E., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3491-3496(2000)
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