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PIGZ Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86VD9
Other Accession NP_079439.2
Clone Names 91119074
Additional Information
Gene ID 80235
Other Names GPI mannosyltransferase 4, 241-, GPI mannosyltransferase IV, GPI-MT-IV, Phosphatidylinositol-glycan biosynthesis class Z protein, PIG-Z, SMP3 homolog, hSMP3, PIGZ, SMP3
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PIGZ
Synonyms SMP3
Function Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers a fourth mannose to some trimannosyl- GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is facultative and only scarcely detected, suggesting that it only exists in some tissues.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Widely expressed at low level, with highest level in brain and colon.
Research Areas
Citations (0)
citation

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Background

The glycosylphosphatidylinositol (GPI) anchor is aglycolipid found on many blood cells that serves to anchor proteinsto the cell surface. This gene encodes a protein that is localizedto the endoplasmic reticulum, and is involved in GPI anchorbiosynthesis. As shown for the yeast homolog, which is a member ofa family of dolichol-phosphate-mannose (Dol-P-Man)-dependentmannosyltransferases, this protein can also add a side-branchingfourth mannose to GPI precursors during the assembly of GPIanchors.

References

Taron, B.W., et al. J. Biol. Chem. 279(34):36083-36092(2004)Eisenhaber, B., et al. Bioessays 25(4):367-385(2003)Oriol, R., et al. Mol. Biol. Evol. 19(9):1451-1463(2002)Grimme, S.J., et al. J. Biol. Chem. 276(29):27731-27739(2001)

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$ 277.78
Cat# BP5778b
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