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C4orf31 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8TB73 |
|---|---|
| Other Accession | NP_078850.3 |
| Clone Names | 91230027 |
| Gene ID | 79625 |
|---|---|
| Other Names | Protein NDNF, Neuron-derived neurotrophic factor, NDNF, C4orf31 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NDNF |
|---|---|
| Synonyms | C4orf31 |
| Function | Secretory protein that plays a role in various cellular processes (PubMed:20969804, PubMed:24706764, PubMed:31883645). Acts as a chemorepellent acting on gonadotropin-releasing hormone (GnRH) expressing neurons regulating their migration to the hypothalamus (PubMed:31883645). Also promotes neuron migration, growth and survival as well as neurite outgrowth and is involved in the development of the olfactory system (PubMed:20969804, PubMed:31883645). May also act through the regulation of growth factors activity and downstream signaling (PubMed:31883645). Also regulates extracellular matrix assembly and cell adhesiveness (By similarity). Promotes endothelial cell survival, vessel formation and plays an important role in the process of revascularization through NOS3-dependent mechanisms (PubMed:24706764). |
| Cellular Location | Secreted |
| Tissue Location | Expressed in neurons along the gonadotropin- releasing hormone (GnRH) expressing neurons migratory route |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Promotes matrix assembly and cell adhesiveness (By similarity).
References
Utine, G.E., et al. Genet. Couns. 17(2):205-209(2006)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)
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