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hCG_2039146 Antibody (Center) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession A6NL88
Other Accession NP_001138648.1
Clone Names 91230099
Additional Information
Gene ID 729956
Other Names Protein shisa-7, Protein shisa-6-like, SHISA7
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SHISA7 (HGNC:35409)
Function Transmembrane protein that regulates gamma-aminobutyric acid type A receptor (GABA(A)R) trafficking, channel deactivation kinetics and pharmacology, necessary for fast inhibitory transmission in the brain. Enhances the action of benzodiazepine, a primary GABA(A)Rs target drug, in the brain. May affect channel kinetics of AMPA-type glutamate receptors (AMPAR), the brain's main excitatory neurotransmitter, necessary for synaptic hippocampal plasticity, and memory recall. May regulate the induction and maintenance of long-term potentiation at Schaffer collaterals/CA3-CA1 excitatory synapses.
Cellular Location Postsynaptic density membrane {ECO:0000250|UniProtKB:Q8C3Q5}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q8C3Q5}. Note=Localizes at GABAergic inhibitory synapses and colocalizes with gephyrin in hippocampal neurons {ECO:0000250|UniProtKB:Q8C3Q5}
Research Areas
Citations (0)
citation

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References

Grimwood, J., et al. Nature 428(6982):529-535(2004)Venter, J.C., et al. Science 291(5507):1304-1351(2001)

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$ 277.78
Cat# BP5815c
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