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C19orf57 Antibody (Center) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q0VDD7 |
|---|---|
| Other Accession | NP_077299.3 |
| Clone Names | 91230229 |
| Gene ID | 79173 |
|---|---|
| Other Names | Uncharacterized protein C19orf57, Pre-T/NK cell-associated protein 3B3, C19orf57 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | BRME1 (HGNC:28153) |
|---|---|
| Synonyms | C19orf57 |
| Function | Meiotic recombination factor component of recombination bridges involved in meiotic double-strand break repair. Modulates the localization of recombinases DMC1:RAD51 to meiotic double-strand break (DSB) sites through the interaction with and stabilization of the BRCA2:HSF2BP complex during meiotic recombination. Indispensable for the DSB repair, homologous synapsis, and crossover formation that are needed for progression past metaphase I, is essential for spermatogenesis and male fertility. |
| Cellular Location | Chromosome {ECO:0000250|UniProtKB:Q6DIA7}. Note=During meiosis, recruited to chromosomes and localizes on recombination sites in a double-strand break-dependent manner. First appears on the chromosome axis at leptotene. Along with the progression of meiotic recombination, released from the axis to form bridge-like structures linking homolog axes before they are synapsed. Finally, located between synapsed homolog axes and on the synaptonemal complex (SC). {ECO:0000250|UniProtKB:Q6DIA7} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)Matsuoka, S., et al. Science 316(5828):1160-1166(2007)Ranes-Goldberg, M.G., et al. J. Immunol. 151(10):5810-5821(1993)
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